In humans, the heart’s sinoatrial node (SAN), acts as the body’s pacemaker. A new study, published Wednesday (July 26) in Science Translational Medicine, reports two backup mechanisms that may prevent ...

Sinoatrial exit block occurs when the action potential initiated by the sinoatrial node is inhibited or completely blocked before it is able to leave the SA node and reach the atrium, and thus no ...

The human heart is a remarkably efficient pump, beating about 100,000 times a day and circulating about 7,500 liters of blood. It is driven by the sinoatrial node, a cluster of pacemaker cells that ...

First, the sinoatrial, or SA, node sets your “resting” heart rate, usually somewhere between 60 and 100 beats per minute. This is the base effort needed to circulate enough blood to sustain ...

Ivabradine is a selective inhibitor of the I f ion channel found in cardiac pacemaker cells of the sinoatrial node. The drug reduces heart rate at rest and during exercise in patients in sinus ...