BACKGROUND: CADASIL is a hereditary form of small-vessel disease caused by mutations within the Notch3 gene. MRI abnormalities have been found both in asymptomatic and symptomatic CADASIL individuals.

The event was put down to a severe hemiplegic migraine (a rare type of migraine that involves temporary weakness on one side ...

Typical MRI findings are T2 weighted hyperintensities ... Only symptomatic therapy is available and thus, as a progressive disease, CADASIL leads to severe dementia and finally to death, commonly ...