Three different hTERT-immortalized human primary renal proximal tubule epithelial cells (RPTEC) were modified and tested for functionality and stable expression of the OAT1, OCT2, and OAT3 proteins.

[21] Many other cells can be seen in urine and are of variable clinical significance. Renal tubule epithelial cells can be oval to columnar in shape, depending on the segment of the tubule they ...

Transform your drug development pipeline with Newcells’ Renal Proximal Tubule Cells Model eBook. This eBook provides insight into the science behind aProximate ™, an innovative proximal tubule ...

continue along the nephron tubule as urine. This eventually passes down to the bladder. In carrying out these processes, the kidney is able to fulfil its functions of regulating the water and ion ...

1 Under the conditions of their experiments they demonstrated that the renal tubules ... urine was considered by them to be hydrogen ions derived from carbonic acid formed in the renal tubular cells.

Retired NBA legend Dwyane Wade revealed his kidney cancer diagnosis on a recent podcast episode. Here's what to know about ...

The work included in vitro renal transporter studies using Newcells' aProximate TM model, comparing proximal tubule cell flux in rats, dogs, and humans. The data was analyzed to provide a ...

Podocytes are crucial for regulating glomerular function, which involves filtering waste and excess water from the blood to ...

Nephrotoxicity, the major complication of long-term therapy with amphotericin B, is attributed to drug-induced renal vasoconstriction plus a direct toxic action on renal tubules. Hypokalemia and ...