Receptor tyrosine kinases (RTKs) are pivotal in both normal cellular functions and cancer progression, activating critical signaling pathways. In cancer therapy, targeted therapies using monoclonal ...
RTKs can activate Ras, a protein that is tethered to the plasma membrane, by causing it to bind GTP. Once activated, Ras can do a variety of things. In this example, it activates an enzymatic ...
The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback