Figure 1: E. coli mRNA decay is activated by the conversion ... or do multiple enzymes act to remove the two phosphates sequentially? Given that RNase E forms a complex (the RNA degradosome ...

Importantly, ManS was produced by a noncanonical biogenesis mechanism: The ribonuclease RNase III, which usually cuts double-stranded RNA, cleaves at a single-stranded region in the mRNA 3'UTR.