Utilizing a cutting-edge electron microscopy technique, the team has unlocked new insight into the intricate folding dance leading to the final shape of RNA molecules. The flexibility of RNA makes ...

Left side of figure shows the process of individual-particle cryo-electron tomography (IPET) where RNA samples are frozen on a grid, then imaged by tilting the sample at different angles.

Understanding these structures with conventional methods, such as cryo-electron microscopy ... conformations once in solution. No large RNA structure database exists that correlates sequence ...

Using cryogenic electron microscopy, Partho Ghosh's lab at UC San Diego has figured out the first steps of this accelerated evolution by visualizing the relevant proteins and RNA. They found that ...

To combat the influenza virus, researchers are investigating ways to destabilize its genome, composed of eight RNA molecules. However, each RNA segment is bound to a complex assembly of proteins that ...