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RAD51 biomarker could complement next-generation sequencing in personalizing prostate cancer treatment
RAD51 is a protein involved in homologous recombination repair (HRR) alterations. Developed in-house by Serra's laboratory, the RAD51 assay is based on the detection of this protein as a ...
Hosted on MSN2mon
RAD51 testing shows promise in personalized early breast cancer treatment
Developed in-house by Serra's laboratory, a test based on the detection of the RAD51 protein as a functional biomarker of homologous recombination repair (HRR) is currently being validated in the ...
Nature1y
Genetic Recombination
RPA has a higher affinity for ssDNA than Rad51, and it therefore can inhibit recombination by blocking Rad51's access to the single strand needed for invasion. In yeast, however, binding of Rad51 ...