Rationale for peptide-centric approaches Although the exact number of human protein products remains ... including phosphorylation and glycosylation 2. Consequently, genes frequently serve as ...

The bottom-up analysis of glycopeptides therefore offers important advantages for glycoprotein characterization, providing information about the structure and composition of the glycans and about the ...

Glycosylation is a common post-translational protein modification and many key ... the selected deactivation of serum IgG with EndoS. Peptide glycosylation can be achieved using a two-step process ...

From these studies we will learn how O-glycosylation is modulated by peptide sequence and neighboring glycosylation and the extent that changes in glycosylation may alter the properties of these ...

bacteria or just lipids or glycans. Sometimes even to the single cell level. With this technology we are able to study the spatial distribution of proteins, peptides and metabolites directly on tissue ...

Peptide glycosylation can be achieved using a two-step process involving EndoA or EndoM. Peptide-N-glycosidase F-deglycosylated monoclonal antibodies can be transported across the placenta and act ...