Mammalian AMP-activated protein kinase (AMPK) was discovered as a protein kinase that switches off lipid synthesis. The yeast orthologue, the SNF1 complex, was discovered in screens for mutations ...

Discover how next-generation kinase inhibitors are transforming clinical therapy byovercoming resistance and enhancing ...

A new review published in Genes & Diseases explores the multifaceted role of FAM20C, a Golgi protein kinase, in disease progression. By highlighting ...

Researchers have discovered a new approach to prostate cancer treatment by combining immunotherapy with PIM1 kinase ...

Protein kinase inhibitors have revolutionized cancer treatment by targeting specific kinases involved in tumor growth and survival. As of 2024, over 80 small-molecule protein kinase inhibitors have ...

Shenzhen Zhongge Biotechnology Co. Ltd. has divulged AMP-activated protein kinase α1β1γ1 activators reported to be useful for the treatment of acute kidney injury, alopecia, chronic kidney disease, ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system. To maintain ...

While it is known that chimeric fusion proteins often drive constitutive kinase signaling in leukemic cells, few data exist revealing how these proteins perturb lymphoid development and contribute ...

Cystic fibrosis is a life-threatening disease predominantly with respiratory symptoms. Most of the subjects with the disease harbor the F508del variant in the CFTR gene that causes the protein to ...

Recombinant Proteins market in terms of revenue was estimated to be worth $2.2 billion in 2023 and is poised to reach $3.2 ...