and computational deconvolution (of their individual effects), empowering the use of phenotypic screening to advance therapeutic discovery. In this Tools of the Trade article, Xinwen Liu describes ...

Phenotypic screening enables researchers to identify molecules that act on disease pathways in cells. Rather than starting with a hypothesis, researchers run unbiased screens for drug candidates ...

Fully definable high content analysis software removes this bottleneck allow for bespoke protocols to be written that will give you phenotypic data on a per object (foci ... large scale screen ...

More information: Nuo Liu et al, Scalable, compressed phenotypic screening using pooled perturbations, Nature Biotechnology ...

Target-based screening has been the method of choice in drug discovery for the past two decades, but phenotypic screening is having something of a renaissance. We look at the advantages and ...

Scientists in Cambridge have developed a new ‘super test’ for prostate cancer to improve screening, diagnosis and ...