Newly emergent prion diseases such as bovine spongiform encephalopathy, variant Creutzfeldt–Jakob disease (CJD), and chronic wasting disease are a source of critical concern to physicians ...

Prion diseases are characterized by abnormal folding of the host’s naturally-occurring ... involve genetic modification—overexpression or mutation of one gene (or set of genes) that mimics some of the ...

iPSC-derived neurons can provide important mechanistic insights into the pathogenesis of genetic prion diseases, and can offer a powerful platform for testing candidate therapeutics," said co ...

The same kind of prion-like seeding and spreading may ... may modulate Alzheimer's disease pathogenesis as well via the microglia, the review in Cell explained. An underlying infectious basis ...

Dr. Patricia Aguilar Calvo's laboratory focuses on the factors that modulate the interaction of misfolded proteins with glycoproteins and the impact in the pathogenesis of prion and Parkinson's ...