In some cases, invasive cancer of the vulva is found below the area affected by Paget’s disease. The most common symptoms are itching and patches of red and white scaly skin on the vulva, similar in ...

Linkage analysis was originally used to identify familial Paget disease genes. One study indicated that about 29% of families with a history of Paget disease have a mutation in the sequestosome 1 ...

Alendronate sodium is a bisphosphonate used to treat Paget disease of bone (PDB). The approved dosage of 40 mg/day for 6 months is generally well tolerated, but esophageal irritation can occur if ...