为解决 Sephin1 作用机制存争议的问题，研究人员开展 Sephin1 相关机制研究。结果发现其通过抑制 PP2A 全酶形成减少 CHOP 表达，抑制细胞死亡。该研究为理解 Sephin1 机制及相关疾病治疗提供新思路，值得科研读者一读。 在细胞的微观世界里，各种生命活动的有序 ...

LIXTE has demonstrated that its first-in-class lead clinical PP2A inhibitor, LB-100, is well-tolerated in cancer patients at doses associated with anti-cancer activity. Based on extensive published ...