It can form either a homodimer (PDGF-BB) or a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), with the dimers linked by disulfide bonds. Mutations in PDGFB have ...

as well as promoting wound healing with growth factors like PDGF-BB. Additionally, the hydrogel proved effective in photothermal chemotherapy. This approach involves using photosensitized ...

as illustrated by platelet-derived growth factor (PDGF)-BB stimulation of different porcine aortic endothelial (PAE) cells (Fig. 2). Wild-type PAE cells do not express human PDGFR, PAE-α cells ...

Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...