[27] Again, validation of this assay in larger, more diverse transplant populations is needed prior to its clinical application. Mixed lymphocyte reaction Blood (PBMC) Recipient PBMCs are cultured ...

proliferation or cytotoxicity Effective in predicting short-term outcome Sensitive Complex technique Cumbersome to perform Enzyme-linked immunospot assay Blood (PBMC) Recipient PBMCs are cultured ...

With its intended use defined, the next stage of CAR+ T assay development is the selection of specimen type; for example, whole blood, bone marrow aspirate or PBMC. The choice of the specimen ...