为探究 PARP 抑制剂耐药机制，研究人员针对 SETD1A 在相关癌细胞中的作用展开研究，发现其可致 ATM 及 BRCA1 缺陷细胞耐药，或为临床提供新方向。 在癌症治疗的战场上，PARP 抑制剂（PARPi）曾被寄予厚望。它就像一颗精准的 “智能炸弹”，专门瞄准那些在 DNA 双链 ...

Other PARP inhibitors have validated the mechanism of action in cancers of the ovary, breast, prostate and pancreas. IDX-1197 has several key advantages over those commercially available PARP ...

We are getting questions from farmers and accountants wondering if Pandemic Assistance Revenue Program (PARP) payments are still going to be made in 2023. Many are tidying up taxes for 2023 ...

Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPis) are promising cancer treatments because they block a cell’s ability to repair DNA damage. Four PARPis are currently approved for use in the ...