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生物通
1 个月
重大突破!溶酶体 NKG7—— 调控 CD8+ T 细胞代谢与命运,开启癌症 ...
动物实验:使用多种小鼠品系,包括 C57BL/6、B6.SJL、Nkg7 基因敲除小鼠、LCMV H2 - Db gp33 特异性 TCR 转基因 P14 小鼠以及 CD8+ T 细胞特异性 NKG7 转基因小鼠等。对小鼠进行病毒感染实验(如感染 LCMV Armstrong 或 LCMV - Clone 13 病毒),观察 NKG7 对 CD8+ T 细胞在体内抗病毒 ...
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