How does addiction work in the brain? Repeated use of a drug changes the wiring of the brain in a number of ways. It stimulates the nucleus accumbens, and overactivity of the nucleus accumbens ...

Already approved for smoking and treatment-resistant depression, brain stimulation is being tested for multiple addictions ...

Addiction is possible ... These changes begin by intensely increasing dopamine levels in the nucleus accumbens, but end up ...

The nucleus accumbens (NAc) is a key structure within ... The correlation to human addiction still requires further ...

Naturally rewarding stimuli (i.e. food, sex, etc) increase the activity of dopamine cells in the mesocorticolimbic dopamine system causing increased dopamine release in brain areas such as the nucleus ...

The brain pleasure centres being targeted in this study - the nucleus accumbens - is also involved in mood, anxiety and depression. That factor is potentially key since many addiction disorders ...

Studies in the lab utilize behavioral models of addiction such as drug self-administration and place conditioning ... Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA ...

This trial examines how CBD might influence alcohol cravings triggered by cues and affect brain activity in the nucleus accumbens, or NAc, a region tied to reward and addiction, which was ...

The nucleus accumbens (NAc) is a brain region that plays a key role in reward, motivation, and addiction. The NAc is rich in endocannabinoids, which are critical for many physiological functions ...

Kutlu's recent research: - The discovery that dopamine release in the nucleus accumbens core specifically ... plasticity could lead to more effective addiction treatments." 2.