A new research perspective was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of ...

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled "Nuclear lipid ...

In the article, researchers reveal that when a cell is faced with a stiff environment, the nuclear lamina -- scaffolding that helps the nucleus keep its shape and structure -- becomes unwrinkled ...

In the article, researchers reveal that when a cell is faced with a stiff environment, the nuclear lamina—scaffolding that helps the nucleus keep its shape and structure—becomes unwrinkled and ...

In the article, researchers reveal that when a cell is faced with a stiff environment, the nuclear lamina — scaffolding that helps the nucleus keep its shape and structure — becomes unwrinkled and ...

Our current model of NE rupture is that disorganization of the nuclear lamina leads to areas of weak membrane that are prone to both chromatin herniation and membrane rupture when force is applied to ...

It is supported by the nuclear lamina (NL), a fibrous protein network composed of lamins, including lamin A (LA) and lamin C (LC). Mechanical stress or genetic abnormalities can cause ruptures in ...

A consistent feature of aging across diverse species is the progressive accumulation of lipid droplets (nLDs) within the nuclear compartment, which ...

More information: Ting-Ching Wang et al, Matrix stiffness drives drop like nuclear deformation and lamin A/C tension-dependent YAP nuclear localization, Nature Communications (2024). DOI: 10.1038 ...