2025年2月25日，复旦大学脑科学研究院杨振纲所带领的研究团队，以“NOTCH, ERK, and SHH signaling respectively control the fate determination of cortical glia ...

To investigate the molecular mechanisms that determine SSPC fate with aging, the researchers collected hindlimb bones from young ... The data also revealed an association between age-related bone ...

It turned out Notch signaling is essential for glia regeneration ... 1 on phagocytic progenitors could be governing the final fate determination of glial cells in planarians.

Taken together, all these results suggest that Hes1 functions downstream to Notch signaling for the suppression of AML development in mice.