While current therapeutic options include chemotherapy and immunotherapy, this study opens new avenues for novel approaches ...

BAFF is required for normal B-cell development. Without BAFF, B-cell development is arrested at the transitional-cell stage, leading to a marked deficiency in late-transitional (T2) B cells ...

B-cell maturation antigen, or BCMA, is selectively expressed when plasma cells differentiate. It is almost absent on memory and naive B cells. The maintenance of long-lived plasma cells involves ...

So B-cell maturation antigen is an evolving field where we have three ways of targeting this receptor, including the antibody direct conjugate, as well as the chimeric antigen receptor T-cell ...

A research team from Osaka University investigates the impact of antioxidant enzymes on specific cell types and their role in ...