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牙龈卟啉单胞菌促口腔癌干细胞特性新机制:NOD1/KLF5 轴调控 SCD1 脂质 ...
为探究牙龈卟啉单胞菌(P. gingivalis)与口腔鳞状细胞癌(OSCC)细胞干性的关系,研究发现其通过 NOD1/KLF5 轴调控 SCD1 脂质合成促进 OSCC 细胞干性,为治疗提供新靶点。 口腔癌,作为一种严重威胁人类健康的恶性肿瘤,近年来其发病率呈上升趋势,给患者带来了 ...
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