When NF-kB is released from its inhibitor I-kB, it increases both inflammation and viral replication. With the help of sufficient selenium naturally, cells lock it safely away in the cytoplasm to ...
The effect was comparable to the inhibition of NF-kB by the NF-kB inhibitor SN 50 and was not due to a reduced binding of TNF-α to its receptor or a decreased surface expression of TNF-α receptors.