Gutierrez’s team infected macrophages generated from human induced pluripotent stem cells with Mtb. Using CRISPR-Cas9 tools, they deleted ATG7 or ATG14 from macrophages and observed increased Mtb ...

Through the process of antigenic variation, P. falciparum expresses different versions of it and escapes immune recognition. 3) Inside macrophages, Mycobacterium tuberculosis dodges intracellular ...

To increase efficacy, the researchers delivered the enzymatic drug inside of host macrophages where mycobacteria grow. In laboratory experiments, the drug was effective against M. tuberculosis and ...

The PPE2 protein of Mycobacterium tuberculosis is secreted during infection and facilitates mycobacterial survival inside the host. The potential mechanism of the progression from latent to active ...

This enables the disease the hide inside the immune cells ... D-induced cathelicidin production and killing of Mycobacterium tuberculosis in macrophages from a patient with a non-functional ...

Specifically, TNF is responsible for triggering the release of molecules called reactive oxygen species (ROS) within alveolar ...