seen as a cross-bridge between actin and myosin filaments in muscle, acts as the motor domain of the molecule and pulls actin filaments along by repetitive conformational changes coupled to ATP ...

It has something to do with a sliding interaction between actin and myosin. In 1954, scientists published two groundbreaking papers describing the molecular basis of muscle contraction.

New research has detailed how UNC45, a protein chaperone, distinguishes between healthy and faulty myosin in muscle cells, ...

UConn physiologist and geneticist Jianjun Sun, a professor in the Department of Physiology and Neurobiology, suspected that actin and myosin—the building blocks of muscles—might play a role in ...

PDUFA Target Action Date Set for September 26, 2025SOUTH SAN FRANCISCO, Calif., Dec. 02, 2024 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated ...

Cytokinetics, Bayer enter collaboration and licensing pact to develop & commercialize aficamten in Japan: South San Francisco, California Wednesday, November 20, 2024, 15:00 Hrs [ ...