Reversing mitochondrial damage could help cure diabetes Regardless of the cell type, the researchers found that damage to the ...

Normal metabolic activity produces reactive oxygen species (ROS) that, if not eliminated, can damage cellular components. As a result, ROS from overactive mitochondria are frequently cited as a source ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

Mitochondria are responsible for creating energy, which fuels cells and keeps them functioning. However, mitochondrial ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, ...

Researchers have identified the transfer of mitochondria with mutated DNA from cancer cells to immune cells as a key ...

Mitochondrial damage is common in metabolic diseases like Diabetes, affecting insulin production and function in patients. Diabetics’ insulin-producing β-cells have abnormal mitochondria, impairing ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

For example, Tobias Dansen and Daan van Soest at the University Medical Center Utrecht tackled the assumption that hydrogen peroxide produced by mitochondria caused DNA damage. Armed with inducible ...