Viral proteins reprogram several processes associated with primary metabolism by interacting with the host’s metabolic enzymes. The methionine cycle (MTC), also known as activated methionine cycle, is ...

Methionine adenosyltransferase 2A (MAT2A), the rate-limiting enzyme in the methionine cycle, catalyzes the formation of S-adenosylmethionine (SAM) from methionine and adenosine triphosphate (ATP).

A study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation ...