A memory engram, or memory trace, is a term for the set of changes in the brain on which a memory is based. These are thought to include changes at the level of the synapses that connect brain cells.

a "locus of engram," but rather are spread fairly uniformly over the cortex. Since HM, however, it has been clear that certain parts of the brain are especially concerned with memory storage ...

This image depicts a single memory engram cell in the hippocampal dentate gyrus region of a mouse model of early Alzheimer's disease. To optically manipulate specific connections to these engram ...

Despite advances in understanding how memories are formed and stored, the retrieval of memories after death remains an elusive and complex challenge. Memory formation is one of the most intricate ...

1 The physical component of a memory consists of activated neurons and synapses formed during an event, collectively called an engram. 3 To study changes in engram cells during forgetting, Autore’s ...

And follow up experiments demonstrated that it was the activation of the memory engram specifically—and not other neurons—that allowed the mice to recall their lost spatial memory. “So, the deprived ...