Further investigations into estrogen signaling mechanisms led to the discovery ... 11)(Fig. 1). This action is almost certainly mediated through a plasma membrane receptor that is present on ...

Potential mechanisms of estrogen-driven carcinogenesis include ... references supporting the corresponding pathway of estrogenic action.

Potential mechanisms of estrogen-driven carcinogenesis include prostatic estrogen receptor-mediated events, epigenetic changes, genotoxicity, hyperprolactinemia and chronic inflammation.

It is well known that, upon stimulation by estrogen, ER-alpha enters the cell nucleus where it mediates the transcription of ...

Steroid hormones are usually assumed to be long ... This change in focus shifted attention away from more rapid mechanisms of steroid action for several decades. Rapid mechanisms can occur within ...