This immunotoxin was shown to induce apoptosis in macrophages that are participating in a chronic inflammatory response in the skin. They further demonstrated that clearance of the inflammatory ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

Research from VIB-UGent identifies lipid-associated macrophages and LAM-like Kupffer cells as critical for liver repair. The study reveals TREM2's role in clearing damaged cells and promoting recovery ...

In addition, the study also demonstrates that the LAM identity is induced in the different macrophage populations through their uptake and clearance of dying cells at the site of injury.