Nature10 个月
Cerebral primitive neuroectodermal tumor in an adult with a heterozygous MSH2 mutation
Diagnosis. Lynch syndrome with a heterozygous germline mutation in MSH2. Management. Debulking of the cerebral tumor, craniospinal axis radiotherapy, and genetic counseling of family. A 30-year ...
icr.ac.uk3 年
Targeted prostate cancer screening could benefit men with inherited cancer syndrome
New research found that annual PSA testing could pick up cases of prostate cancer up to eight times as often in men with genetic hallmarks of Lynch syndrome – faults in genes like MSH2 and MSH6 – than ...