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MMP-9 抑制剂 SB-3CT 调控星形胶质细胞脂质代谢助力缺血性脑卒中治疗
为探究 MMP-9 抑制剂 SB-3CT 对缺血性脑卒中的作用,研究发现其可调控脂质代谢,影响神经恢复。 缺血性脑卒中急性期,基质金属蛋白酶 - 9(MMP-9)活性激增。MMP-9 虽参与自然修复过程,但会破坏血脑屏障(BBB),加重水肿和炎症。脑卒中发作后,MMP-9 主要由中性 ...
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