the mechanisms of MHC expression--explored at several levels including the transcription and translation of MHC genes and the insertion of MHC protein molecules into plasma membranes; the effect of ...

Unlike CARs, TCRs can also recognize intracellular proteins, as they bind to peptides presented on the cell surface by major histocompatibility complex (MHC) proteins. Matthias Leisegang ...

MHC Class I and MHC Class II Antigen Processing Pathways Antigen processing and therefore the immune response to vaccines is generally divided into two systems, although considerable cross-over ...

“As part of our study, we searched for yet unknown receptors and came across a protein called IRGQ, which is specifically responsible for ensuring the quality control of the MHC-I radio masts ...

thus promoting glycolysis and reducing the expression of MHC in the tumor. EZH2 is also capable of methylating a number of non-histone protein substrates, such as STAT3, which promotes PD-L1 ...

An intracellular sensor that tracks the quality of so-called MHC-I molecules which aid the immune system in identifying and ...

Multiplexed-engineered, iPSC-derived CAR T Cell Targets Proteins Expressed on Cancer Cells in Response to Cellular Stress and ...