Rett syndrome is caused by mutations of the MECP2 gene located on the X chromosome. Children with Rett initially show typical ...

Alteration in the expression of methyl-CpG-binding protein 2 (MeCP2) has been linked to a number of neurological disorders, including Rett syndrome (RTT). A recent modifier screen in flies has ...

The team focused on engineering the parasites to deliver the MeCP2 protein, which is already seen as a promising treatment for Rett syndrome, a debilitating neurological disorder caused by ...

According to the research by Dr. Edilene Siqueira and Dr. Sònia Guil, loss of function of MeCP2 – hallmark of the disease – affects the long non-coding RNA NEAT1, promoting the malfunction of one of ...