为探究 m6A 调控的铁死亡基因在 T2DM 中的作用，西北妇女儿童医院等单位的研究人员开展相关研究。他们鉴定出生物标志物，揭示了潜在机制。该研究为 T2DM 临床诊疗提供新思路，推荐科研读者阅读。 在当今社会，糖尿病就像一个隐藏在人群中的 “健康杀手 ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both ...

Adding these methyl groups enhances RNA stability; however, their removal by enzymes such as FTO can promote development of tumors. FTO was the first identified m6A demethylase and has been shown ...

Adding these methyl groups enhances RNA stability; however, their removal by enzymes such as FTO can promote development of tumors. FTO was the first identified m6A demethylase and has been shown ...

and N6-methyladenosine (m6A) modifications enable circRNAs to undergo cap-independent translation. The resulting proteins influence a range of cellular processes, including those linked to cancer ...

a. 18097 inhibits FTO to promote substrate mRNAs m6A level in breast cancer. b. HUHS015 disturbs ALKBH3 functioning as prostate cancer antigen 1. c. R-2HG prevents FTO removing m6A from MYC/CEBPα ...