Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...

研究人员主要运用了生物信息分析、细胞实验等关键技术方法。生物信息分析方面，从 Gene Expression Omnibus（GEO）数据库检索 POAG 相关数据集，经筛选和预处理后进行分析。细胞实验则包括培养原代人小梁网细胞（HTMCs），进行细胞转染、RNA 提取及定量逆转录聚合 ...

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny ...

Scientists have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the progression of ...

In others, the m6A tags appeared to be active players, helping cancer cells multiply, migrate and invade new tissue. One of the key discoveries involved a gene called VCAN, which produces a ...

LINC00901 is an m6A-modified lncRNA and its high level is associated with poor prognosis of PDAC patients. (A) MeRIP and lncRNA profiling identified five candidate lncRNAs in MIA PaCa-2 cells ...