为了揭开这个神秘的面纱，来自西北妇女儿童医院麻醉科等单位的研究人员在《Hereditas》期刊上发表了一篇名为 “Identification of biomarkers and mechanism exploration of ferroptosis related genes regulated by m6A in type 2 diabetes mellitus” 的论文。他们通过研究发现了 ...

然而，m6A修饰及其关键“书写酶”METTL3在MASLD中的具体作用尚不清楚 ... MASLD小鼠肝脏组织中有386个差异表达基因（DEGs），其中211个上调，175个下调。基因本体（Gene Ontology, GO）和京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）富集分析表明 ...

LINC00901 is an m6A-modified lncRNA and its high level is associated with poor prognosis of PDAC patients. (A) MeRIP and lncRNA profiling identified five candidate lncRNAs in MIA PaCa-2 cells ...

Binding of both the RNA-binding protein TDP-43 and the m6A RNA modification chemical tag has been found to be altered in genes that are dysregulated in HD. Further, TDP-43 pathology, classically ...

Epigenetics and epitranscriptomics play a crucial role in modifying gene expression without altering gene sequence. N6-methyladenosine (m6A) is one such mechanism, where methyl groups are added to ...