investigated how mTOR activity in phagocytes regulates the innate inflammatory response ... exposure to lipopolysaccharide (LPS). Unexpectedly, rapamycin-mediated inhibition of mTOR caused ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.