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巨噬细胞中 LPS 诱导线粒体超氧化物的产生机制及对免疫调控的关键意义
为解决 LPS 诱导巨噬细胞线粒体超氧化物产生机制不明等问题,英国研究人员开展相关研究。结果发现其由反向电子传递驱动,且 RET 产生的 mtROS 调节 IL-1β 释放。该研究对理解巨噬细胞免疫功能意义重大,推荐一读。 在人体的免疫系统中,巨噬细胞可是个 ...
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