该研究开发了一种新型脂质纳米颗粒（LNP）系统——MK16 BLNP，能够突破血脑屏障，通过静脉注射将 mRNA 递送至大脑中枢神经系统中的神经元和星形 ...

Moderna’s SpikeVax vaccine is based on LNP-encapsulated nucleoside-modified mRNA encoding the full-length SARS-Cov-2 spike protein. During the non-clinical phase, the vaccine's immunogenicity ...

kit-based solutions that offer high-quality integrity and purity results for a wide range of sizes Take control of determining mRNA-LNP encapsulation efficiency with an intuitive capillary ...

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

The eTheRNA research team encapsulated a novel mixture of mRNA ... We also showed that the Triplet mRNA LNP therapy didn't work in the absence of T cells." The results in mouse models are very ...

This publication demonstrates how the SoloVPE System was used to measure the total mRNA concentration after LNP encapsulation. The method was developed and qualified by assessing the specificity ...

格隆汇6月25日丨石药集团(01093.HK)宣布，集团开发的首款基于mRNA-LNP的嵌合抗原受体(CAR)-T细胞注射液(SYS6020)("该产品")已获中华人民共和国国家药品 ...

In a study in Nature Communications, Mitchell, Padilla and their collaborators demonstrate that BEND lipids improve LNP delivery of mRNA and gene-editing tools, in some cases by as much as tenfold.