Thanks in part to LL Cool J ‘s “Mama Said Knock You Out,” Pfizer’s new Super Bowl commercial will leave viewers feeling hyped ...

The rapper’s 1991 hit “Mama Said Knock You Out” provides the soundtrack for Pfizer’s cancer-busting commercial.

LL Cool J (left:) in the "Mama Said Knock You Out" video; (right) In 2024.

LL Cool J is bringing back an iconic hit for a Super Bowl ad that packs a punch — literally. In Pfizer’s “Knock Out" ad, a young cancer patient is first shown laying in a hospital bed ...

Pfizer/Youtube Pfizer's Super Bowl commercial features LL Cool J's hit "Mama Said Knock You Out" That’s when “Don’t call it a comeback” — the memorable first lines of LL Cool J’s 1991 hit, “Mama Said ...