The NetworKIN algorithm consists of two steps. In the first step, each phosphorylation site is assigned to one or more kinase families, based on the intrinsic preference of kinases for consensus ...
thermophila has the largest kinome of any unicellular eukaryote, and almost 3.8% of the MAC genome encodes a kinase. A number of kinases (630) could not be assigned to a known family but several ...
The largest commercial kinase panel available, scanMAX panel, contains a set of 468 kinases covering AGC, CAMK, CMGC, CK1, STE, TK, TKL, lipid and atypical kinase families, plus important mutant forms ...
As a non-receptor tyrosine kinase, TYK2 is a member of the JAK kinase family, which is an important kinase on the JAK-STAT signaling pathway and plays an important role in the pathogenesis of ...