A universal kinase platform HTRF KinEASE screenings limit assay development time and are easily miniaturizable as well as flexible, meaning the assay can be performed under a wide range of kinase ...
Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.
With over 15 years of experience in kinase drug discovery, DiscoverX offers the largest collection of nearly 500 biochemical and cell-based kinase assays. KINOMEscan® technology, our novel kinase ...
In recent years, however, several new assays and techniques have emerged that will allow drug developers to identify more selective kinase inhibitors capable of targeting a greater range of human ...
SignalChem Biotech, part of Sino Biological, offers one of the largest active enzyme collections in the world and specializes ...
The US Food and Drug Administration (FDA) has granted breakthrough device designation for Acrivon Therapeutics’ ACR-368 ...
The PamChips® are blocked in 2% Bovine Serum Albumin (BSA). Following protein concentration determination (by BCA assay), 5-10 μg of protein for the PTK chip (~1 μg for the STK) will be loaded per ...