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衰老与抗病毒防御新解:STAT1 修饰转换如何左右老年人免疫防线?
为探究衰老如何调节蛋白质翻译后修饰(PTMs)影响机体抗病毒防御能力,研究人员开展 STAT1 修饰相关研究。发现衰老影响 STAT1 的 Kbhb 和 O-GlcNAc 修饰,小分子化合物和果糖可干预。该研究为提升老年人抗病毒能力提供策略,值得一读。 2025年,中国科学院的研究 ...
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