intracellular inclusions in motor neurons, and in some cases within the astrocytes surrounding them as well 3. These aggregates are intensely immunoreactive with antibodies against SOD1 ...

The build up of mutant HTT into intracellular deposits known as inclusion bodies as well as the selective death of striatal and cortical neurons are hallmarks of this disease. However, the effect ...

Cornea verticillata attributable to glycosphingolipid accumulation associated with Fabry's disease also demonstrates bright reflective intracellular inclusions located within the basal epithelial ...