Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands.

Intracellular recording is an electrophysiology technique that uses a microelectrode inserted into a single cell, usually a neuron, to measure its electrical activity. The parallel intracellular ...

But in 2008, Mukherjee stumbled across a new and much faster way to cause intracellular mayhem. Studying bacterial interactions with actin is still throwing up new mysteries. These microbes all enjoy ...

The result? There are high-value intracellular targets that neither modality can hit. Without being able to reach these ‘undruggable’ intracellular targets, many of the best-validated drivers ...

Various microbes, including several human pathogens, hijack the cell’s skeleton, membranes, and protein-making machinery to make themselves at home. Intracellular bacteria use various tricks to ...

Entrada Therapeutics' innovative Endosomal Escape Vehicle platform, poised to revolutionize drug delivery. Click here to read ...

Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Following the conclusion of the presentation, a replay will be available for 30 days on the “Events and Presentations” page of Larimar’s website.