a patient’s own immune system. Since the 1990s, immune stimulants like interferon-γ have been used to enhance the effectiveness of cancer treatment and prevent relapse. But immunotherapy began ...

a protein made by an interferon-stimulating gene, in protecting against replication stress and promoting genomic stability. “Together, these studies shed new light on how the Mre11 complex works to ...

Interferons are signaling molecules that ... it can trigger the innate immune system in ways that can promote cancer,” Dr. Petrini says. By shedding light on the interrelationships between ...

Interferons are signaling molecules that ... it can trigger the innate immune system in ways that can promote cancer," Dr. Petrini says. By shedding light on the interrelationships between these ...

But many of the tactics the virus and the immune system use in this contest have remained a mystery, making it challenging to design medicines to help patients defeat the virus. Interferons ...

Casanova’s team concluded that IRF7’s failure to ramp up production of interferons was likely responsible for the patient’s severe ... but Casanova says this is consistent with other observations that ...

A treatment for hepatitis C is the drug interferon-alpha which challenges the immune system in the same way as a powerful infection. The team measured fatigue and immune markers before ...

But many of the tactics the virus and the immune system use in this contest have remained a mystery, making it challenging to design medicines to help patients defeat the virus. Interferons ...

MSK researchers discovered that the innate immune system's chronic activation due to issues in the Mre11 complex can lead to ...