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CTCF介导的染色质拓扑结构进化差异驱动人类转录创新
《自然·通讯》推荐:华南理工大学等团队通过跨物种ChIA-PET技术解析灵长类CTCF介导的染色质拓扑差异,揭示人类特异性CCD边界和CTCF环通过重塑增强子-启动子互作调控基因表达的新机制,为理解神经发育疾病(如自闭症)和自身免疫病(如系统性红斑 ...
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