Objectives Tendinopathy is a frequent clinical problem and represents an extraordinary health economic and socioeconomic burden with high unmet medical needs. Recent clinical evidence suggests ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

Opioid use during pregnancy—whether of highly addictive drugs like fentanyl or controlled opioids like buprenorphine—doubles ...

The integration of cytokines into stem cell and organoid research has significantly advanced drug discovery by enabling more ...

To solve this puzzle, we studied brain inflammation in the context ... as damage to the muscle fibers, this pathway directly causes fatigue. Since the key cytokine involved in brain-to-muscle ...

ISM001-055 was shown to have attenuated cellular senescence through the suppression of various aging processes, thus showing potential as a senomorphic drug.

Researchers found that furanodienone (FDN), a compound in ginger, activates pregnane X receptor (PXR) to reduce gut ...

IL-4Rα Pathway: IL-4 and IL-13 are primarily involved in immune responses mediated ... These key measures include the inhibition of inflammatory cytokine release and the reduction of tissue ...