This upregulation of IRF4 expression by IGF-1 treatment of MM cells is abrogated when FAIM expression ... the data was performed using Student’s t-test. Group difference with P<0.05 was ...

promotes regulatory T cell (Treg) development by activating the Aldh1a2/Raldh2 gene in dendritic cells through the aryl hydrocarbon receptor (AhR) and PU.1/IRF4 pathways. Raldh2, encoded by the ...